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Catalog/Chelohart

Chelohart

Also known as A-14 heart peptide · cardiac peptide complex

A natural heart-muscle peptide complex (Cytomax A-14) — the extract-based counterpart to Cardiogen, targeting cardiac tissue.

Research refreshed

Overview

Chelohart is a natural peptide complex extracted from cardiac muscle (peptide complex A-14, from the heart of young calves or pigs), part of the Russian Cytomax / Revilab bioregulator line. It is the extract-based cardiac counterpart to the synthetic tetrapeptide Cardiogen (Ala-Glu-Asp-Arg), marketed within the Khavinson tradition for heart-muscle support.

Background

Chelohart is the heart-directed natural bioregulator of the Cytomax / Revilab line, extracted from cardiac muscle tissue. It pairs with Cardiogen, the synthetic Ala-Glu-Asp-Arg tetrapeptide already catalogued: Chelohart is the natural cardiac extract, Cardiogen the defined synthetic short peptide modeled on the same tissue.

As a tissue extract it is a standardized polypeptide fraction with no single molecular formula or sequence. Its claims — supporting contractile function and cellular repair in cardiac tissue — come from the same concentrated research tradition as the rest of the series, with limited independent replication, and it is not FDA-approved.

Mechanism

Proposed tissue-selective (bioregulator) modulation of cardiomyocyte gene expression, in the same lineage as the synthetic heart peptide Cardiogen.

Key research findings

  • Cardiac bioregulator — a natural heart-muscle peptide extract (complex A-14), the extract counterpart to synthetic Cardiogen.
  • Cardiomyocyte focus — marketed for contractile function and cellular repair in heart tissue within Khavinson protocols.
  • A tissue extract — a polypeptide fraction with no single formula or sequence.
  • Evidence quality — concentrated in one research tradition; preliminary. Not FDA-approved.

How Chelohart is made

Behind every vial of Chelohart is the same exacting pipeline every research peptide runs — but the chemistry plays out differently for this molecule. Here is how Chelohart, specifically, is brought into being.

  1. On paper first

    Chelohart begins not as a powder but as a specification. Before a single bond is made, the target sequence, salt form, and purity threshold are written down as the contract the finished material must meet.

  2. Built residue by residue

    Chelohart is assembled by solid-phase peptide synthesis — the chain grows one protected residue at a time on resin, and what you fail to build cleanly here you pay to remove later.

  3. Purity is won here

    The crude mixture — Chelohart plus its deletions and side products — is then separated on preparative HPLC, and where the cut is taken decides the difference between a genuinely pure peptide and a barely-passable one.

  4. Proven, then protected

    A real batch of Chelohart proves itself: identity confirmed by mass spectrometry, purity read directly off an analytical HPLC trace, water and counterion content measured. That batch-specific certificate of analysis is the only honest way to know what is actually in a vial of Chelohart — and a short, cold, accountable chain of custody is how that purity survives the trip to your bench.

Walk the full synthesis pipeline

Handling, storage & why purity is hard

Chelohart is a natural cardiac-muscle peptide extract (complex A-14), a fractionated polypeptide preparation rather than a synthesized peptide. Consistency and characterization of the extract, not coupling chemistry, determine its quality.

Moderate synthesisTissue extract

Don't judge a vial by its cake. A fluffy, good-looking lyophilized powder reflects bulking agents and freeze-drying parameters — not purity. Insist on a batch-specific certificate of analysis.

How peptides are made — the full pipeline

Research areas

  • Cardiac health
  • Aging biology
  • Peptide bioregulators

Research-area guides

Frequently asked questions

What is Chelohart?+

Chelohart is a natural heart-muscle peptide complex (Cytomax A-14), marketed for cardiac support — the extract-based counterpart to the synthetic peptide Cardiogen.

How does it relate to Cardiogen?+

Chelohart is the natural cardiac extract; Cardiogen is the defined synthetic tetrapeptide (Ala-Glu-Asp-Arg) modeled on the same tissue.

Does it have a molecular formula?+

No — it is a tissue extract (a polypeptide fraction), so it has no single sequence or molecular formula.

Is Chelohart approved?+

No — it is a research compound / supplement, not FDA-approved. This page is a research and educational reference.

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Dosing protocols, mechanism, comparisons, and the latest trials — citation-backed answers grounded in PubMed, PubChem, and ClinicalTrials.gov.