# Testagen

> Synthetic Lys-Glu-Asp-Gly tetrapeptide studied as a testis / reproductive-tissue bioregulator.

- Also known as: Lys-Glu-Asp-Gly, KEDG tetrapeptide
- Class: Reproductive, Bioregulators
- FDA approved: No
- Canonical page: https://americanpeptide.com/catalog/testagen

## Overview

Testagen is a synthetic tetrapeptide (Lys-Glu-Asp-Gly) in the Khavinson short-peptide bioregulator series, directed at reproductive (testicular) tissue and studied for effects on male reproductive and hormonal markers.

Testagen (Lys-Glu-Asp-Gly) is the reproductive-tissue member of the defined short-peptide bioregulator family — the synthetic, single-sequence counterpart to older testis extracts, framed around age-related decline in male reproductive function within the originating research tradition.

Reported research examined markers of testicular and reproductive function in models, consistent with the class hypothesis of tissue-selective transcriptional modulation. As with the rest of the series, the evidence is concentrated in one research tradition with limited independent replication, and it is not FDA-approved.

## Mechanism

Proposed gene-regulatory modulation of gene expression in reproductive tissue.

## Chemistry

| Property | Value |
| --- | --- |
| Molecular formula | C17H29N5O9 |
| Molecular weight | 447.4 Da |

## Sequence

```
KEDG
```

## Research areas

Studied in: Reproductive function, Aging biology, Peptide bioregulators.

Guides on this site:

- [Longevity & Aging](https://americanpeptide.com/research-areas/longevity-aging): Peptides studied across the aging axis — senescence, NAD+, and resilience.
- [Sexual & Reproductive Health](https://americanpeptide.com/research-areas/sexual-reproductive): Peptides studied across the HPG axis and CNS sexual-response pathways.
- [Peptide Bioregulators](https://americanpeptide.com/research-areas/bioregulators): Short, tissue-specific peptides proposed to regulate gene expression — the Khavinson series.

## Key research

- Reproductive focus — studied for effects on testicular and reproductive-tissue markers in preclinical models.
- Class mechanism — proposed short peptide–DNA interaction driving tissue-selective gene expression.
- A defined tetrapeptide — the synthetic single-sequence counterpart to older testis extracts.
- Evidence quality — single-tradition and largely preclinical; preliminary. Not FDA-approved.

## Storage, handling & synthesis

**Synthesis.** Testagen (Lys-Glu-Asp-Gly) is a tetrapeptide made by routine solid-phase synthesis with no disulfides or modifications, like the other Khavinson short peptides. Purity is governed by ordinary deletion-sequence and counterion control.

## FAQs

### What is Testagen?

Testagen is a synthetic Lys-Glu-Asp-Gly tetrapeptide studied as a testis / reproductive-tissue bioregulator in the Khavinson short-peptide series.

### What tissue is it associated with?

Reproductive (testicular) tissue — each bioregulator in the series is framed around a specific target tissue.

### How strong is the evidence?

It is concentrated in a single research tradition and is largely preclinical, so findings are preliminary. This page is a research and educational reference.

## Latest research

Recent trials and publications mentioning Testagen, pulled automatically from ClinicalTrials.gov and PubMed (unfiltered search results, refreshed daily).

### Recent trials

- [Product Transference Study of Testagen™ TDS®-Testosterone](https://clinicaltrials.gov/study/NCT02733133) — NOT_YET_RECRUITING · PHASE2 · NCT02733133

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Source: AmericanPeptide.com — https://americanpeptide.com/catalog/testagen
Data license: CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). Attribution: AmericanPeptide.com.
Research reference only — computational and educational content, not medical advice.