# Chelohart

> A natural heart-muscle peptide complex (Cytomax A-14) — the extract-based counterpart to Cardiogen, targeting cardiac tissue.

- Also known as: A-14 heart peptide, cardiac peptide complex
- Class: Bioregulators
- FDA approved: No
- Canonical page: https://americanpeptide.com/catalog/chelohart

## Overview

Chelohart is a natural peptide complex extracted from cardiac muscle (peptide complex A-14, from the heart of young calves or pigs), part of the Russian Cytomax / Revilab bioregulator line. It is the extract-based cardiac counterpart to the synthetic tetrapeptide Cardiogen (Ala-Glu-Asp-Arg), marketed within the Khavinson tradition for heart-muscle support.

Chelohart is the heart-directed natural bioregulator of the Cytomax / Revilab line, extracted from cardiac muscle tissue. It pairs with Cardiogen, the synthetic Ala-Glu-Asp-Arg tetrapeptide already catalogued: Chelohart is the natural cardiac extract, Cardiogen the defined synthetic short peptide modeled on the same tissue.

As a tissue extract it is a standardized polypeptide fraction with no single molecular formula or sequence. Its claims — supporting contractile function and cellular repair in cardiac tissue — come from the same concentrated research tradition as the rest of the series, with limited independent replication, and it is not FDA-approved.

## Mechanism

Proposed tissue-selective (bioregulator) modulation of cardiomyocyte gene expression, in the same lineage as the synthetic heart peptide Cardiogen.

## Research areas

Studied in: Cardiac health, Aging biology, Peptide bioregulators.

Guides on this site:

- [Longevity & Aging](https://americanpeptide.com/research-areas/longevity-aging): Peptides studied across the aging axis — senescence, NAD+, and resilience.
- [Peptide Bioregulators](https://americanpeptide.com/research-areas/bioregulators): Short, tissue-specific peptides proposed to regulate gene expression — the Khavinson series.

## Key research

- Cardiac bioregulator — a natural heart-muscle peptide extract (complex A-14), the extract counterpart to synthetic Cardiogen.
- Cardiomyocyte focus — marketed for contractile function and cellular repair in heart tissue within Khavinson protocols.
- A tissue extract — a polypeptide fraction with no single formula or sequence.
- Evidence quality — concentrated in one research tradition; preliminary. Not FDA-approved.

## Storage, handling & synthesis

**Synthesis.** Chelohart is a natural cardiac-muscle peptide extract (complex A-14), a fractionated polypeptide preparation rather than a synthesized peptide. Consistency and characterization of the extract, not coupling chemistry, determine its quality.

## FAQs

### What is Chelohart?

Chelohart is a natural heart-muscle peptide complex (Cytomax A-14), marketed for cardiac support — the extract-based counterpart to the synthetic peptide Cardiogen.

### How does it relate to Cardiogen?

Chelohart is the natural cardiac extract; Cardiogen is the defined synthetic tetrapeptide (Ala-Glu-Asp-Arg) modeled on the same tissue.

### Does it have a molecular formula?

No — it is a tissue extract (a polypeptide fraction), so it has no single sequence or molecular formula.

### Is Chelohart approved?

No — it is a research compound / supplement, not FDA-approved. This page is a research and educational reference.

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Source: AmericanPeptide.com — https://americanpeptide.com/catalog/chelohart
Data license: CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). Attribution: AmericanPeptide.com.
Research reference only — computational and educational content, not medical advice.